1.PQQ（Pyrroloquinoline Quinone)
PQQ,also known as pyrroloquinoline quinone , is a new type of water-soluble vitamin known as the king of immunity in the global biomedical community. It is the strongest antioxidant substance in the world and is an oxidoreductase cofactor that exists in some microorganisms, plants, and animal tissues.
2.Functions of PQQ
When we are fighting against aging, we often talk about antioxidant activity. To achieve antioxidant activity, it is necessary to start from two aspects to reduce already oxidized cells to prevent them from being oxidized.
2.1 Oxidoreductase
This is an enzyme that can reduce oxidized cells back, such as the well-known superoxide dismutase SOD. The enzyme can reduce the content of peroxides through catalysis. It is highly efficient, but the enzyme is fragile and easy to inactivate.
SOD molecular structure
O2-, also known as superoxide anion radicals, is a naturally occurring intermediate product in various physiological reactions of organisms. It is a type of reactive oxygen species with extremely strong oxidation ability and is one of the important factors of biological oxygen toxicity. It can aggregate into surface, heart, blood vessels, liver, and brain cells. It is the culprit that causes human aging and diseases.
2.2 Antioxidant
Antioxidants are a component that we often use in anti-aging, such as vitamins C and E. They can reduce the damage of oxygen ions to cells.
Although these antioxidants have strong antioxidant effects, most of them cannot circulate indefinitely like enzymes, and they can cause losses when clearing free radicals. We need to constantly supplement them, but they are more stable and better preserved compared to enzymes.
The PQQ that we will introduce today is a special component. Firstly, it is a coenzyme of oxidoreductase, which can promote the enzyme's function by binding to its active center, thereby helping our cells improve their oxidized state and further resist aging.
Secondly, PQQ itself is also an antioxidant. Moreover, PQQ has a very strong antioxidant capacity, far exceeding that of VC and other antioxidants. Moreover, it has been found during experiments that PQQ can also promote the growth and repair of mitochondria, thereby improving cell energy metabolism and preventing mitochondrial aging.
Finally, PQQ can also stimulate neuronal growth, thereby promoting neuroprotection and improving cognitive function.
In addition, due to its ability to activate longevity proteins like NMN to a certain extent, PQQ has quickly become popular in the anti-aging and antioxidant circles as a rising star in the field of anti-aging.
PQQ is a relatively new nutrient, but there is already a large amount of experimental data proving its significant effects on the human body.
he experiment shows that oral PQQ can increase the cerebral blood flow in the prefrontal cortex, which may prevent the decline of brain function in the elderly, especially attention and working memory;
In another clinical trial, it was found that the average low-density lipoprotein decreased slightly from 136.1 to 127.0 mg/dL in the experimental group receiving PQQ.
In addition, some clinical trials have found that PQQ can promote sleep and reduce inflammatory markers.
At the same time, a large amount of experimental data further indicates the promoting effect of PQQ on mitochondria, which can further help us improve the efficacy of mitochondria, thereby making the human body younger and more energetic.
3.Application of PQQ
At present, the common PQQ supplement products on the market are mainly aimed at brain health, sleep aid, energy supplementation, oral beauty, pregnancy aid, and other aspects. They are often used in combination with various raw materials such as MNM, coenzyme Q10, Ginkgo biloba extract, PS, etc.
In fact, as a new type of raw material, PQQ has been recognized for its positive role in nutrition and health. Due to its powerful functions, high safety, and good stability, it has broad development prospects in the field of functional food.
In recent years, with the continuous deepening of cognition, PQQ has achieved the most comprehensive efficacy certification and is widely used as a dietary supplement or food in countries and regions such as the United States, Europe, and Asia. With the continuous deepening of consumer awareness, it is believed that PQQ as a new food ingredient will create a new world in the market